Hormones and Homeostasis

1	Endocrine system	D.5.U1: Endocrine glands secrete hormones directly into the bloodstream (Oxford Biology Course Companion page 694). State the function of endocrine glands. State the function of hormones. D.5.U7: Hormones secreted by the pituitary control growth, developmental changes, reproduction and homeostasis (Oxford Biology Course Companion page 697). Outline the role of the hypothalamus as a link between nervous and endocrine systems. List hormones secreted by the anterior and posterior pituitary. D.5.U6: The hypothalamus controls hormone secretion by the anterior and posterior lobes of the pituitary gland (Oxford Biology Course Companion page 697). Draw a diagram to illustrate the relationship between the hypothalamus and pituitary. Describe how releasing factors regulate anterior pituitary action. Describe how neurosecretory cells carry hormones to the posterior pituitary. Outline how negative feedback is involved in the secretion of ADH from the posterior pituitary.	Homeostasis and feedback loops Feedback loop jamboard (answers) Homer-ostasis activity Homer-ostasis word sort Thailand Cave Rescue Intro to hormones and glands notes Labeling glands task About the hypothalamus The hypothalamus video clip The hypothalamus and negative feedback video clip Anterior pituitary notes Anterior pituitary CFU Posterior pituitary notes Posterior pituitary CFU Pituitary hormones flow chart
2	Hormone action	D.5.U2: Steroid hormones bind to receptor proteins in the cytoplasm of the target cell to form a receptor–hormone complex (Oxford Biology Course Companion page 695). Describe the mechanism of steroid hormone action. List two example steroid hormones. D.5.U3: The receptor–hormone complex promotes the transcription of specific genes (Oxford Biology Course Companion page 696). List locations at which a steroid hormone binds its receptor. Outline one example of a steroid hormone promoting transcription of specific genes. D.5.U4: Peptide hormones bind to receptors in the plasma membrane of the target cell (Oxford Biology Course Companion page 696). State the location at which a protein hormone binds its receptor. List two example protein hormones. Define “second messenger system.” D.5.U5: Binding of hormones to membrane receptors activates a cascade mediated by a second messenger inside the cell (Oxford Biology Course Companion page 696). List the two most common second messengers.	Protein and Steroid hormone notes Hormone action handwritten notes Signal transduction video clip Pathways with friends Hormone action CFU Hormones jigsaw Hormones spoons game A&B: SciAm Cell Communication reading
3	Glucose homeostasis	6.6.U1: Insulin and glucagon are secreted by beta and alpha cells of the pancreas respectively to control blood glucose concentrations (Oxford Biology Course Companion page 329). Explain the control of blood glucose concentration, including the roles of glucagon, insulin and the alpha and beta cells in the pancreatic islets. 6.6.A1: Causes and treatment of Type I and Type II diabetes (Oxford Biology Course Companion page 330). Distinguish between causes of type I and type II diabetes. Distinguish between treatment of type I and type II diabetes. D.1.U8: Overweight individuals are more likely to suffer hypertension and type II diabetes (Oxford Biology Course Companion page 664). Outline the causes of the two types of diabetes mellitus. List risk factors associated with type II diabetes. State symptoms of type II diabetes. List cardiovascular effects of type II diabetes.	Glucose homeostasis and how insulin works Handwritten glucose homeostasis Blood glucose regulation video clip Blood glucose quizizz review History of diabetes Diabetes notes Diabetes diagnosis skit Diabetes quizizz review Diagnosis Diabetes (students and teacher) Glucose tolerance test results and questions Data collection form for daily rhythms Analyzing SHS data for hunger and eating A&B: Artificial pancreas A&B: Sawbones Diabetes Podcast
4	Metabolic homeostasis	6.6.U2: Thyroxin is secreted by the thyroid gland to regulate the metabolic rate and help control body temperature (Oxford Biology Course Companion page 331). Describe the structure and function of thyroxin. Outline thyroxin’s role in body temperature regulation. List symptoms of thyroxin deficiency. D.5.NOS: Cooperation and collaboration between groups of scientists—the International Council for the Control of Iodine Deficiency Disorders includes a number of scientists who work to eliminate the harm done by iodine deficiency (Oxford Biology Course Companion page 695). Outline consequences of iodine deficiency. State the goal of the ICCIDD.	Notes: thyroxine Thyroid troubles case study part 1 part 2 Part 3 Part 4 What’s wrong with Timothy case study Chemical Eric case study Hot and Bothered case study Thyroid hormone and oxygen consumption A&B: Sawbones Goiter podcast A&B: what’s making a young girl forgetful? Ted Ed: How does the thyroid manage your metabolism?
5	Appetite control	D.1.U7: Appetite is controlled by a centre in the hypothalamus (Oxford Biology Course Companion page 664). Describe how hormones and the appetite control center regulate a desire to eat. 6.6.U3: Leptin is secreted by cells in adipose tissue and acts on the hypothalamus of the brain to inhibit appetite (Oxford Biology Course Companion page 332). State that leptin is a protein hormone. Outline the mechanism of action of leptin. Describe the role and discovery of the ob allele in obese mice. 6.6.A2: Testing of leptin on patients with clinical obesity and reasons for the failure to control the disease (Oxford Biology Course Companion page 332). Explain the double blind study that tested the effect of leptin treatment on human obesity. Outline role of leptin resistance in human obesity.	Leptin notes Leptin handwritten notes How the Hormone Leptin Helps Regulate Appetite I NOVA Leptin CFU A&B: Are you hungry? A&B: the hunger hormone How the Hormone Leptin Helps Regulate Appetite I NOVA I PBS
6	Circadian rhythm	6.6.U4: Melatonin is secreted by the pineal gland to control circadian rhythms (Oxford Biology Course Companion page 333). Define circadian rhythm. Describe the secretion and action of melatonin. Outline the mechanism that regulates melatonin secretion in response to the day-night cycle. 6.6.A3: Causes of jet lag and use of melatonin to alleviate it (Oxford Biology Course Companion page 334). State symptoms of jet lag. Outline the biological cause of jet lag. Describe use of melatonin in treatment for jet lag	Melatonin notes Melatonin handwritten notes Analyzing SHS student data for sleep
7	Growth	D.5.A1: Some athletes take growth hormones to build muscles (Oxford Biology Course Companion page 699). State that growth hormone is a peptide hormone. Outline the mechanism of action of growth hormone. Evaluate the use of growth hormones by athletes	Growth Hormone notes
8	Temperature Regulation	Not currently taught	Thermoregulation notes A&B: How to Help Your Body Adjust to Cold Weather
9	Wrap Up and review		The Greatest Show endocrine disorders Hormones review 1-pager Quizizz review 1 Quizizz review 2 - hormones Kahoot review Final knowledge audit